Interesting study showing that people who use 5-MeO in a supportive context are much more likely to report mystical-type experiences (with the enduring benefits associated with the latter) than people who use it in a non supportive context. I'm sure we're all well aware of the importance of set and setting when it comes to psychedelic use, and even when using a substance as powerful as 5-MeO where one may well transcend both their set and setting, this still very much applies.
Study:Sepeda et al. (2019)
Inhaled 5-methoxy-N,N-dimethyltryptamine: Supportive context associated with positive acute and enduring effects. Journal of Psychedelic Studies, DOI: 10.1556/2054.2019.033.
Full paper can be accessed at:
https://akademiai.com/doi/pdf/10.1556/2054.2019.033