**5-MeO-DMT Survey Study**

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Have you tried 5-MeO-DMT?

Want to help us understand your experience with this substance, including the short- and long-term benefits and other experiences?
Please consider reading more about our project by clicking this link!

We anticipate that it will take you no longer than 20 minutes to fill out the survey. Your participation is completely anonymous and voluntary. As an incentive for participating, and as a way to “pay it forward,” we will donate $2.00 per person (up to $250.00) to the Multidisciplinary Association of Psychedelic Studies as a way to say thank you for your time.
If you are interested in participating or would like to read more about the study, please click the link below to the secure study site.

https://www.surveygizmo.com/s3/3421646/5-MeO-DMT-Public-Survey

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Update!
You can now see the preliminary data from this survey here: https://www.researchgate.net/publication/321832479_5-Methoxy-NN-Dimethyltryptamine_5-MeO-DMT_Patterns_of_use_motives_for_consumption_and_acute_subjective_effects

Background/Aim: 5-Methoxy-N,N-Dimethyltryptamine (5-MeO-DMT) is the main psychoactive ingredient of bufo alvarius toad venom and is present in a variety of plants/shrubs. Anecdotal reports are that synthetic and organic preparations of 5-MeO are used for spiritual and recreational motives and may have psychotherapeutic benefit. However, there is no published evidence about the epidemiology of 5-MeO consumption, limiting understanding of the scope of use and possible harms/benefits of consumption. Therefore, we examined patterns of use, motivations for consumption, and acute subjective effects of 5-MeO-DMT among English-speaking 5-MeO-DMT users.

Method: Using internet-based advertisements, we recruited 515 respondents (Mage=35.4, SD=11.7; Male=79%; White/Caucasian=86%; United States=42%) to complete a web-based survey.

Results: Most people consumed 5-MeO-DMT infrequently (once a year or less), with the motivation of spiritual exploration, and consumed 5-MeO-DMT less than 4 times in their lifetime. Less than half of the sample (39%) reported repeated consumption in the same session, and very low rates of craving (8%), or legal (1%), medical (1%), or psychiatric (1%) problems due to 5-MeO-DMT use were reported. Most respondents (>80%) reported a variety of acute experiences (e.g., awe or awesomeness, amazement, loss of time and space, and difficulty putting experience into words) and relatively fewer (40%-66%) experienced acute challenging experiences (e.g., fear, anxiousness, felt like they were dead or dying). Furthermore, of those who reporting being diagnosed with psychiatric disorders, most reported that 5-MeO-DMT contributed to a decrease in symptoms related to post-traumatic stress disorder (79%), depression (77%), anxiety (69%), and substance use (~63%).

Conclusion: Findings suggest that 5-MeO-DMT is used infrequently, primarily for spiritual exploration, has low addiction liability, and might have psychotherapeutic effects. However, there are no published studies examining the safety of 5-MeO administration in humans. Therefore, we recommend that future research examine the safety and pharmacokinetics of 5-MeO-DMT administration in humans using rigorous experimental designs.