I would again suggest that this be moved to the Questions section.
That being said, dealing with fear as it comes into any powerful entheogenic experience is best dealt with by trusting that this is the right time. If it doesn't feel like the right time, then don't do it. Simple as that. If you are doing any substance because you want to "get" something from it, that is driven by your ego. If you are humbly approaching the experience with a willingness and openness to learn about whatever comes up, then that is the best mindset to go into anything with. This experience, like Flux said, is about the totality of consciousness. So it is a process of understanding and becoming All.
Everyone will have their own relationship to the experience, but I highly recommend adequate preparation be done before taking this substance. In the swimming analogy, you need to be a proficient swimmer before you try to swim in a tidal wave. Strengthen your swimming legs by sitting in unassisted mindful meditation for 15, 30, 45 minutes building up to an hour. In those meditations, become comfortable with the discomfort that arises. Become acquainted with the observer which simply observes all mental phenomena in peaceful awareness. Move through the difficulty by allowing it to happen and see what it is like to sit through meditations that feel like torture. Why all this work? Because 5-MeO-DMT is like sitting in a car moving at 500 miles per hour. If you are not fully aware and at the wheel, the experience can veer off very quickly and can turn into something very much like a train wreck. It can hinder your spiritual progress or even set you back.
There is nothing to fear from the molecule or the experience, but there is definitely a risk and there are real harms that can come from improper use, inadequate preparation, and incompetent sources of support following something of this magnitude.
I am not here to either encourage you or discourage you, but to simply share information so that you can be adequately educated about what you are choosing to undertake. Gerry and Octavio downplay the risks and dangers and thus have many patients who have struggled with integration. I have spoken with several of them. While they have administered the medicine to thousands of people, they have not done so responsibly. It is like LSD in the 60s. Psychedelics are not for everyone, but in the 60s and 70s the idea was that if everyone in the world got "turned on" by LSD, the world would become this magically better place. It does not work like that, not with LSD, not with psilocybin, not with 5-MeO-DMT. People have to be ready to experience these catalysts and not have any expectation that the catalyst will do the work for them. It won't. Only the work the individual does in the following months, years, etc will prove the changes that were suggested by the medicine.
So deeply question yourself. Sit with the deepest fears you have surrounding this medicine. Wait until you know FOR SURE, deep in your heart, that you are ready for this. Make sure that you have support for you after this experience, whether it is super positive or difficult, or neither. Know that there are MANY paths to enlightenment, and that the seeking of enlightenment is itself a very slippery road. Enlightenment is not some thing that is attained, it is something that unfolds within the self. And as soon as one thinks they are enlightened, they are not. As soon as one grasps for it, it is gone.
I hope this is helpful and know that this message is delivered with the greatest love, reverence, and respect for your journey and the journey of all other souls.
May you find the eternal joy, happiness, and peace you seek.