Author Topic: MDMA + Bufo  (Read 44 times)

Offline Blackbird

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MDMA + Bufo
« on: March 17, 2018, 09:42:07 AM »
Dear friends,


Any thoughts on the combination of MDMA and Bufo?
Thinking around 80-10mg of MDMA (I am 80kg), and 10-20mg of Bufo around peak with redosing.


Wholeness <3


M



Offline HumbleVoyager

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Re: MDMA + Bufo
« Reply #1 on: March 17, 2018, 01:38:04 PM »
I personally have not come across any information regarding the combination of Bufo with MDMA, though I have heard of people combining synthetic 5-MeO-DMT with MDMA.

In the interest of harm reduction, it is important to cover some concerns that might arise from this type of combination. The main concern with this combination is the load it may have on the heart, as both substances increase heart rate significantly. If anything, I would say that if you are still thinking of doing it, taking the Bufo at the end of the MDMA session, when the MDMA is wearing off instead of at the peak. The peak of the MDMA experience is correlated with elevated heart rate and anecdotally 5-MeO-DMT does the same. More research has to be done on the effects of 5-MeO-DMT in humans to know for sure.

We would want to reduce the chances for cardiotoxicity as much as possible, so taking 5-MeO-DMT at the peak of an MDMA experience seems unsafe from a medical standpoint.

If you look on Figure 2 in the paper, you can see where the heart rate begins to go back down. This may be a safer point to do the combination if you still plan on doing so. We don't know much about how these substances synergize either, so the presence of MDMA's effects in the system could augment the increased heart rate that comes with 5-MeO-DMT use.

I would strongly recommend not doing this if there are any sorts of heart problems in the individuals attempting this combination.

I hope this information has been helpful. :)

Sources of information:
Acute Effects of MDMA on Autonomic Cardiac Activity and Their Relation to Subjective Pro-social and Stimulant Effects
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634859/

Offline Blackbird

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Re: MDMA + Bufo
« Reply #2 on: March 18, 2018, 03:40:58 AM »
Thank you,


We went ahead, and it was a very nice experience.
Ca 1 g. cubensis + 100mg MDMDA, redosing after about 2 hours, 50 mg.
Smoked 10mg Bufo in two rounds around 3 hours after start.

Physical body seemed to get along fine, and the rest of the bodies were thrilled.
Did not feel tempting to do higher dose though.
Interesting from a tantric point of view, remember your prayers!

1love

 <3

Offline HumbleVoyager

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Re: MDMA + Bufo
« Reply #3 on: March 18, 2018, 09:21:24 AM »
Thank you,


We went ahead, and it was a very nice experience.
Ca 1 g. cubensis + 100mg MDMDA, redosing after about 2 hours, 50 mg.
Smoked 10mg Bufo in two rounds around 3 hours after start.

Physical body seemed to get along fine, and the rest of the bodies were thrilled.
Did not feel tempting to do higher dose though.
Interesting from a tantric point of view, remember your prayers!

1love

 <3

Wonderful to hear this went well! What do you feel the bufo added to the experience?
It appears that 10mg bufo is safe with that MDMA, but perhaps not at a higher dose. I would estimate that 10mg bufo is equal to about .5-1.5mg 5-MeO-DMT, so a reasonably low dose for the experiment. Do let us know what it added and thank you for sharing your experience with us <3