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Messages - Handshake

#1
Introductions/Newbies / Re: thank you for existing
February 10, 2026, 09:17:23 AM
Welcome to the 5 Hive noodlebowl!

So wonderful to have you here and look forward to the conversations that you will bring and contribute to!

5 is truly a unique experience, some might even argue that it is almost in its own class of molecule.
#2
Thank you for sharing this so openly. I really appreciate how you're holding both the awe and the humility of the experience. The way you describe the dissolution and then the clarity before reconnecting with your body captures something many people struggle to put into words.

One thing I'd gently offer is that there isn't really a universal timeline for how long "effects last." Some people feel meaningful shifts for years after one session. Others find that the acute memory fades but the deeper reorganization continues in subtle ways. Framing it as "most people need a reminder after a year" can sometimes unintentionally plant an expectation that something is supposed to wear off. In my experience, what endures most reliably is what gets integrated, not what gets repeated.

A lot of people describe that first encounter as climbing the mountain. Subsequent sessions, when they happen, often feel less like going higher and more like seeing the same landscape from a different angle. Sometimes that brings new insight. Sometimes it simply confirms what was already known. And sometimes it becomes clear that the real work is happening in ordinary life, not in returning to the peak.

I really resonate with your question of "What now?" That's often the most important phase. If there's no sense of need, that's actually a very grounded place to be. The impulse to repeat can come from devotion, curiosity, avoidance, habit, or genuine calling. It can take some honest self-inquiry to discern which is operating.

Some people who revisit do so with very specific intentions around patterns they've noticed resurfacing. Others find that repetition doesn't add much and instead deepen their practice through therapy, community, service, or contemplative work. There isn't a right answer.

If you never do it again and feel complete, that's valid. If you return in a year and it feels aligned and intentional, that's valid too. The more interesting question, in my view, is how the experience is shaping how you relate to others, to your nervous system, to your values, and to your daily life.

Curious what shifts, if any, you've noticed in how you move through the world.
#3
Poetry and Art / Re: Ceramic Bufo
February 06, 2026, 08:43:28 PM
Beautiful piece!
#4
Science / Re: Clinical study on 5-MeO-DMT
February 06, 2026, 07:53:17 PM
Thanks for posting this. I find it interesting too. At the same time, I sometimes wonder whether it's really the studies that legitimize the molecule, or whether it's the long-standing relationships people have had with it that have inspired researchers to finally take it seriously.
#5
Welcome! May I ask which practices you used to help with reactivations?
#6
They do need to be used very carefully, and even then it may be possible for the vape solution to become more concentrated over time, and in some cases it's impossible to know what the actual concentration is in vape pens. There are some low dose protocols for using 5meo vape pens carefully but they depend heavily on carefully tracking the concentration of the vape pens, tracking precise dose timing, etc.

They have the potential to be safe, but the norm is sadly to aim for higher concentrations in vape pens, shooting for a "one-hit breakthrough."
#7
Hello, please note that this is a harm reduction forum and not a place to find facilitators. Forum members are welcome to ask questions about how to determine a suitable facilitator, but we discourage finding and vetting of facilitators on this forum due to the anonymous nature of this platform.

I wish you the best in this search and hope that you can find resources elsewhere.

Also keep in mind that 5-MeO-DMT is illegal where you live, and therefore asking for a facilitator on a clearnet site puts both you and the facilitator at risk.
#8
This project is part of their legacy, and there's some great information about the use and benefits of low dose 5meo. https://patternproject.substack.com/
#9
Here's the full text for you :)
#10
Hey everyone,

I was informed today that on August 6th Marcus suffered a major stroke and passed away on August 22nd.

A GoFundMe has been created on behalf of Marcus and his wife Geffen, to offset those expenses and to provide ongoing financial support.

Marcus, along with his close friend Bill Atkinson (who passed away in June of this year), revolutionized the use of 5-MeO-DMT perhaps most notably through an Erowid article published under the name Grace Within, which made 5meodmt vape pens a possibility, and shared that information freely, along with sharing the insights of the value of low-dose 5meo. This was something that we had spoken about on several occasions, and it was really heartening that they came to know and share the value of the lower dose range.

Please consider sharing the GoFundMe, and donating if you're in a position to do so.

https://gofund.me/e826e216

I'm open to any questions or any clarification you may be interested in.

Thank you,
Handshake
<3  _/|\_
#11
General Discussion / Re: Long-term Impact of 5-MeO-DMT
August 27, 2025, 09:33:59 PM
Really well put, Lopsided.

My experience has been similar. Once you see the bigger picture, you know what's there. It becomes an inner knowing, just like you remember a hike that you've been on or a waterfall you've sat by. And yet like you said, nothing "magic" happens aside from this new awareness. You still are you, with your gifts and your drawbacks, your hang ups and the challenges you face. We still have to work on our daily lives. Our relationships, our politics, and even the process of knowing ourselves as we grow and evolve.

I have found that there are times in life where using psychedelics (in this case 5meo) gives us greater insight and awareness. It helps us slow down and remember the nondual perspective, let go of the things we don't need to hold onto anymore, and keep moving towards what's good. It can connect us to our intuition, and show us various paths ahead.

I have found that 5meo has been a powerful tool for all of those things, and it has also taught me a lot about getting out there and really living. And sometimes that's a long integration. But over time, and after really immersing yourself in the drama(s) of life, you may start to find those same truths and same perspectives that you touched during these journeys. That process takes time, patience, and a willingness to keep turning towards what is challenging. We have to be willing to let the water smooth the stone.

Thanks for opening this discussion, I enjoyed getting to reflect on this!
#12
Donate / Re: How to donate?
February 27, 2025, 09:30:59 AM
So far we have gotten no donations  :-\
#13
Donate / Re: How to donate?
December 17, 2024, 06:14:30 AM
Thank you very much!

For reference, our upcoming server fee in January will be about $300, which will cover costs until January 2027.

Any additional donations will go towards ongoing upkeep, moderation, and upgrade of the forums.

_/|\_  <3  _/|\_
#14
Donate / How to donate?
December 16, 2024, 09:43:09 AM
You may donate via bitcoin using the attached QR code here:


You can also pay with cash using CashApp:
https://cash.app/$Handshake5Hive
#15
General Discussion / Re: Intravenous Injection ROA
February 26, 2024, 09:47:23 AM
Quote from: Inquirer on June 15, 2023, 12:44:51 PMAnybody have experience using an intravenous ROA on a 5-MeO-DMT salt? I'd love to hear experiences in comparison to other ROAs such as vaped, IM, etc. Also interested in dosing. From the few reports I've read, it sounds like a very small amount of material is needed compared to other methods.

There are quite a few reports on IV use of 5-MeO-DMT, and while it seems to be worthwhile, it is so similar to vaporization that it may be best to simply take it via IM, thus allowing for a slower onset and smoother experience overall, most similar to insufflation or rectal admin. Seems that dosage would be the same as Shulgin's experiments, documented in TiHKAL.