Author Topic: A Fatal Intoxication Following the Ingestion of 5-MeO-DMT in an ayahuasca prep.  (Read 918 times)

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Sklerov J, Levine B, Moore KA, King T & Fowler A, 2005, 'A Fatal Intoxication Following the Ingestion of 5-Methoxy-N,N-Dimethyltryptamine in an Ayahuasca Preparation', Journal of Analytical Toxicology, vol. 29, no.8, pp. 38-41, DOI: 10.1093/jat/29.8.838, https://www.researchgate.net/publication/7414522_A_Fatal_Intoxication_Following_the_Ingestion_of_5-Methoxy-NN-Dimethyltryptamine_in_an_Ayahuasca_Preparation

Abstract

A case of a 25-year-old white male who was found dead the morning after consuming herbal extracts containing β-carbolines and hallucinogenic tryptamines is presented. No anatomic cause of death was found at autopsy. Toxicologic analysis of the heart blood identified N,N-dimethyltryptamine (0.02 mg/L), 5-methoxy-N,N-dimethyltryptamine (1.88 mg/L), tetrahydroharmine (0.38 mg/L), harmaline (0.07 mg/L), and harmine (0.17 mg/L). All substances were extracted by a single-step n-butyl chloride extraction following alkalinization with borate buffer. Detection and quantitation was performed using liquid chromatography-electrospray mass spectrometry. The medical examiner ruled that the cause of death was hallucinogenic amine intoxication, and the manner of death was undetermined.